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Do women over 40 need lower GLP-1 doses

In part this was because a set of experiments conducted in dogs between 1939 and 1940 cast doubt about the existence of incretin

Retatrutide is an investigational once-weekly triple agonist that targets GLP-1, GIP, and glucagon receptors

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Of note, the prevalence of HF varied across these trials from 9% to 24%, and HF events were considered a secondary endpoint

Int J Mol Sci 22:9922