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Sanyal and colleagues reported a phase 2a, randomized, placebo-controlled trial in adults with metabolic dysfunction-associated steatotic liver disease in Nature Medicine in 2024

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Research suggests that the medication, a glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptor agonist, originally developed to manage type 2 diabetes, may be able to treat a wide range of conditions involving impulse control, like binge eating disorder

doi: 10.1097/ico.0000000000000408 295 Jones-JordanLAWallineJJSinnottLTKymesSMZadnikK

HNF4A regulates the formation of hepatic progenitor cells from human iPSC-derived endoderm by facilitating efficient recruitment of RNA pol II