Benzodiazepines and Other CNS Depressants Due to additive pharmacologic effect, the concomitant use of benzodiazepines and other CNS depressants, such as benzodiazepines and other sedative hypnotics, anxiolytics, and tranquilizers, muscle relaxants, general anesthetics, antipsychotics, gabapentinoids (gabapentin or pregabalin), and other opioids, including alcohol, can increase the risk of hypotension, respiratory depression, profound sedation, coma, and death
Lpez-Ortiz et al., 2023
Liczne badania fazy III dowiody ich wysokiej skutecznoci w obnianiu poziomu hemoglobiny glikowanej (HbA1c) typowo o okoo 11,5 punktu procentowego (warto bezwzgldna) z poziomu wyjciowego, a w przypadku najsilniejszych analogw nawet do ~1,8% (Semaglutide versus dulaglutide once weekly in patients with type 2 diabetes (SUSTAIN 7): a randomised, open-label, phase 3b trial PubMed) (Efficacy and safety of once-weekly semaglutide 1.0mg vs once-daily liraglutide 1.2mg as add-on to 1-3 oral antidiabetic drugs in subjects with type 2 diabetes (SUSTAIN 10) PubMed)
The customer acknowledges that there are risks in the handling, use, and distribution of these products, and certifies that it has the proper equipment, facilities, and personnel for managing those risks
Laboratory testing (complete blood count, erythrocyte sedimentation rate, C-reactive protein, thyroid function) with normal results excludes inflammatory, autoimmune, or endocrine disorders, but doesnt define the underlying diagnosis when its FM
Although rare, patients with a history of skin sensitivity or allergies should be monitored closely for any adverse reactions
