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It stimulates insulin secretion from pancreatic beta cells in a glucose-dependent manner, meaning it only triggers insulin release when blood glucose levels are elevated

Osna et al., 2022

Demonstrated positive response defined as 5% reduction from baseline body weight (adults) or baseline BMI (pediatrics), or maintenance of weight loss with continued participation in a weight management program that includes lifestyle modification, exercise, and reduced calorie diet

The American Journal of Medicine

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GLP-1 medications carry FDA warnings about potential risks including pancreatitis, gallbladder disease, and acute kidney injury with dehydration