Moreno refers to these patients as super responders. They're losing about one to two pounds per week, their blood pressure and cholesterol are all improving and their sleep apnea is getting better, he says
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But maintaining weight loss after transitioning off GLP-1s requires improving the systems that regulate hunger, energy, muscle mass, blood sugar, recovery, hormones, inflammation, and metabolic flexibility
Restore movement patterns gradually
Foundational work appears in journals including Lancet HIV, AIDS, and JCEM, with multiple phase 2 and phase 3 clinical research papers examining endpoints in HIV-associated lipodystrophy and visceral adipose tissue research.
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