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10.1016/j.carbpol.2020.116874 45 GaoM.ZhangW.MaY.LiuT.WangS.ChenS.et al (2025)

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Thus, while up to 70% of PNA mice displayed irregular cyclicity, characterized by the appearance of only one generation of (mainly persistent regressing) corpora lutea, 100% of PNA mice treated with metformin showed regular ovarian cyclicity, denoted by the presence of two generations of corpora lutea, as a sign of preserved regular ovulations (Fig