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CAI in PWS is not well understood, as studies have reported varying results (ranging from 0% to 60%) using different dynamic tests, such as the insulin tolerance test (ITT), metyrapone test (MT), glucagon test (GT), and the currently most used low-dose and standard dose Synacthen stimulation test (LDSST and SDSST) ( Table 1 ) (5162)

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Regular use for at least 36 months provides the best long-term support

Yoo M, Cho S, Shin S, Kim JM, Park HG, Cho S, Hwang YK, Park DH

Kao ACC, Spitzer S, Anthony DC, Lennox B, Burnet PWJ