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In the compositions of comparative example 1, when HPMC polymer is used, gel formation did not take place but the precipitation was observed as provided in figure 2 and the trials failed

Supplementary Figure S2 shows that HaCaT cells had an apparent cytotoxic effect with the treatment of 1,600 M of H 2 O 2 , while HFF-1 showed obvious cytotoxicity at 800 M of H 2 O 2 after 2 h incubation

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Additionally, a few studies on obese patients found that carnitine supplementation improved blood glucose regulation and lipid metabolism, which may indirectly influence fat distribution over time