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By measuring the ratio of heavy isotope-labelled peptides in urine samples using liquid chromatography (LC)-MS in multiple reaction monitoring (MRM) mode, we observed significantly higher Ggt1 levels in the OVX rats than in the control rats (Figure 3C, peptide determination results are shown in Supplementary Tables S9)

9 This is why the present article describes molecular identity, research history and regulatory context but does not provide benefits, treatment claims or consumer purchasing guidance

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