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This phenotype is consistent with the concept that smaller cells are primarily engaged in proliferation, whereas larger cells often shift to alternative metabolic activities, diverting energy from replication to other cellular processes (Vander Heiden et al., 2009)

Because your body uses and excretes B12 rather than storing unlimited amounts, consistent timing helps keep your energy and focus steady instead of peaking and crashing. Many people find that taking B12 late in the day can make them feel more alert right when they are trying to wind down, which may interfere with sleep

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