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Vitamin B12 is a water-soluble vitamin that contains the mineral cobalt and exists in several forms

The same lack of controlled trials applies to TB-500

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Clinicians must also avoid intravenous administration in the presence of severe sino-atrial, atrioventricular, or intraventricular conduction block in the absence of functional pacemaker support, as well as in classic Adams-Stokes or Wolff-Parkinson-White syndromes, where suppression of accessory pathways may paradoxically precipitate fatal arrhythmias

PMC8615275