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(3) Inhibiting Adipose Tissue Inflammation and Improving the Adipose Microenvironment In obesity, adipose tissue develops chronic lowgrade inflammation with abundant release of proinflammatory factors (such as TNF and IL6), disrupting the adipose microenvironment, further worsening fat metabolic abnormalities and insulin resistance, and forming a vicious cycle

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Popular Medications Available Semaglutide, marketed under brand names like Wegovy and Ozempic, has shown significant success in clinical trials, leading to substantial weight loss in participants

PubMed Thompson JL et al