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Before this work, we knew the ER needed to stay oxidized to fold proteins correctly, but the machinery responsible for maintaining that balance was essentially a black box, says Gad

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Pretreatment with a tyrosine kinase inhibitor or with a serine/threonine kinase inhibitor inhibited both the oxidative burst and the induction of GST in the incompatible interaction (Rajasekhar et al., 1999)

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