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Semaglutide also tends to produce more rapid and substantial weight loss than older GLP-1 medications, which aligns with the weight-loss-driven telogen effluvium hypothesis
349,350 This change suggests that liraglutide not only inhibits inflammation and cartilage degradation but may also promote the synthesis and accumulation of cartilage matrix, thereby helping to protect and repair joint cartilage
Regular follow-up with healthcare providers, including A1c testing approximately 3 months after discontinuation for patients with diabetes, is recommended
For patients also taking insulin or sulfonylureas, alcohol may increase hypoglycemia risk
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