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The escalating prevalence, particularly during the last decades, has made NAFLD the second most common cause of liver transplantation in the United States [5]

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The field of metal-based composites research took off in the 1970s when scientists tried combining metals and alloys with ceramic reinforcements through powder metallurgy, rheocasting, and stir casting, all of which produced intriguing outcomes [45, 46]

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Pharmacokinetic characterization in porcine models demonstrated an intravenous half-life of approximately 3 minutes, with rapid degradation via sequential amino-terminal amino acid removal and confirmed oral bioavailability