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thus, GCL is considered the rate-limiting enzyme [6]

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After 90 min, there was a marked reduction in SIN concentrations across all organs, with the liver and kidneys maintaining relatively higher levels, suggesting these as key organs for metabolism and elimination

The maternal genome is active up to the 2-cell embryo, and the embryonal genome plays its role from the 2-cell embryo stage [46]

590 Furthermore, -syn oligomers induce lipid peroxidation, while inhibition of lipid peroxidation and reduction of iron-dependent free radical accumulation can reduce the neuronal toxicity induced by -syn oligomers, suggesting the role of ferroptosis in PD