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Start at the lowest dose, escalate every 4 to 6 weeks, use all available side effect management strategies

The half-life is approximately 6 days

The median back skin and the back muscles were incised longitudinally at two locations on the left and right sides to expose the adrenal glands and were resected with scissors

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10.1038/302716a0 9 BornerT.ShaulsonE

Degradation products are not always visible