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Particular caution is warranted with NSAIDs (such as ibuprofen), which can affect kidney function, especially when combined with dehydration seek pharmacist or GP advice before using these medications if you're experiencing gastrointestinal symptoms

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Toyoda M, Kaira K, Ohshima Y, Ishioka NS, Shino M, Sakakura K, et al

Several people interviewed for this story say that since starting a GLP-1, they have either completely come off their mental health medication or are considering it

On April 9, 2026, Health Canada issued a public advisory warning consumers about unauthorized injectable peptide drugs, naming BPC-157 among the products it has seized