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Glutathione peroxidase 1 (GPX1) is one of the most abundant members of the GPXs family that protects cell from oxidative damage and maintains the balance of intracellular redox systems (Sharma et al., 2021a), GPX1 is a gatekeeper restraining the oncogenic power of mitochondrial ROS generated by superoxide dismutase 2 (SOD2) (Wen et al., 2014)

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Equally, the authors acknowledge the continued support of the University of Zululand Research Committee for payment of APC and other resources made available

Lillys triple agonist, retatrutide, delivered weight loss of up to an average of 71.2 lbs along with substantial relief from osteoarthritis pain in first successful phase 3 trial