Role of advanced glycation end products in cellular signaling
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Similar results were observed when tumours were implanted into the flanks of mice, a result that suggests that this phenotype is not specific to the mammary gland environment (Extended Data Fig
Certainly, hyperglycaemia (or oral glucose tolerance) did not turn out to be a strong predictor of GLP-1 secretion, suggesting that other characteristics of type 2 diabetic patients not represented by elevated glucose concentrations in the fasting or postprandial state may determine GLP-1 secretion, although opinions differ [54]