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First, it is plausible that DPI penetration to the sites of lucigenin action may be limited in intact cells (this would explain why DPI was so much more effective in suppressing the lucigenin chemiluminescence observed in cell-free partially purified CYB5R preparations, compared with transiently transfected intact cells [35]) or alternatively, a second DPI-insensitive enzyme system may exist in whole cells, that is also capable of activating lucigenin

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10.1210/jc.2017-01922 24 BelenichevI.AliyevaO.PopazovaO.BukhtiyarovaN

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UniProt: the Universal Protein Knowledgebase in 2023