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Because TAM was administered systemically, this delayed weight gain in female mice could be because of TAM effects on multiple central or peripheral tissues

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Sono anche detti a lunga durata dazione ( long-acting ) in quanto, una volta raggiunto lo stato stazionario, mantengono concentrazioni ematiche costantemente elevate che determinano una continua stimolazione di GLP-1R e solo fluttuazioni minori tra una somministrazione e laltra