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DOI.org (Crossref), Najjar, Rami S., et al

This resulted in high levels of bacterial endotoxins, sending several patients to the hospital with serious reactions (FDA safety notice)

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Distilled water is commonly used in laboratories, aquariums, and certain medical applications due to its purity

J Androl 24(6):S17S37 Burchardt T, Burchardt M, Karden J, Buttyan R, Shabsigh A, de la Taille A, Ng PY, Anastasiadis AG, Shabsigh R (2000) Reduction of endothelial and smooth muscle density in the corpora cavernosa of the streptozotocin induced diabetic rat

They are not always negative adverse reactions