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Individuals with active cancer or recent cancer history face theoretical concerns about angiogenesis promotion

The rodent BDNF gene was initially described by Aid et al (20) and comprises at least eight distinct promoters, initiating the transcription of multiple distinct mRNA transcripts, comprising four 5-exons (IIV) linked to separate promoters, and one 3-exon (V) that contains the entire open reading frame for the BDNF protein

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