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Gibofsky A (2014) Epidemiology, pathophysiology, and diagnosis of rheumatoid arthritis: a synopsis

[2] It is estimated that over 10% of cellular glucose is metabolized via this pathway, which notably oxidizes glucose without directly producing or consuming ATP

A more detailed understanding of the switch from fetal to adult hemoglobin, and identification of transcriptional regulators such as BCL11A, aided by the developments in genetic and genomic platforms, provide hope that genomic-based approaches for therapeutic reactivation of HbF may soon be possible (Vinjamur et al., 2018)

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For immunohistochemical staining with 4HNE and ferritin, the same antibodies and protocol were used as for human brain sections