Symptoms of a B12 deficiency include: Excessive fatigue Nerve problems (pain or abnormal sensations like numbness or tingling) Glossitis (tongue inflammation) Low numbers of white blood cells and red blood cells Vitamin B12 deficiency can be diagnosed with a blood test
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However, some patients experience persistent but manageable symptoms like mild constipation or occasional nausea, particularly if they resume old eating patterns with large portions or high-fat foods
Patients with certain genetic profiles may experience more intense nausea or longer adjustment windows
Methods The present retrospective cohort was conducted on adult patients referred between November 2022 and December 2023 to a tertiary referral hospital in Shiraz, Iran
These data confirm, as previously described in the literature [4, 5, 8, 48, 57], that sulfur dioxide is also a powerful inhibitor of laccase