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Harpagoside-induced anaphylactic reaction in an IgE-independent manner both in vitro and in vivo

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This compound primarily functions by binding to sugar moieties, thereby forming the backbone structure of flavonoid compounds, including rutin, hesperidin, naringin, and citrusin

No major toxicological red flags have been identified in preclinical studies

By raising mitochondrial respiration and oxidative phosphorylation, glucocorticoids directly cause neuronal OS (62)

For example, if a patient needs 2500 mcg and the vial has 1000 mcg/mL, you need 2.5 mL