THE SIMPLE PLAN What to do first What to add What works best together FOUNDATION Protected Lean Muscle (LOAD) If you do one thing while on a GLP-1, it should be protecting lean muscle
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Special populations and timing considerations Certain groups face unique timing challenges that deserve specific attention
Titration Schedules Importance of Titration Jumping straight to 8mg or 12mg would cause severe nausea and vomiting for most people
Natural GLP-1 is produced by the body, however, as we discussed earlier, it has a very short lifespan, and patients with T2D and other metabolic disorders can experience reduced secretion of the hormone or reduced sensitivity to it
Early comparisons of retatrutide vs tirzepatide suggest this triple action may deliver greater weight loss results, though direct head-to-head trials have not been completed