Intrathecal injection of exendin-4 reduced pain sensitivity as assessed by the von Frey test and decreased neuroinflammation, with reduced TNF, IL-1 and IL-6 levels, thus demonstrating that analgesic effects of GLP-1R signalling were directly correlated with its anti-neuroinflammation activity [89]
While theres limited research on GLP-1 drugs specifically for psoriatic arthritis, we know inflammation plays a role in both psoriatic arthritis and diabetes
Retatrutide's stronger fat-loss effect may be overkill for maintenance
If its high, your doctor can talk to you about steps to lower it
The company anticipates that these requirements will not be fulfilled within 2024
13 In addition to filing and being granted patents for the compound semaglutide, Novo Nordisk has filed and been granted patents covering derivative compounds of semaglutide