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When you are looking to support something as complex as metabolism, you want to ensure the tools you are using are actually reaching their destination

Gibson and MacFarlane, ed

Repairing the gut barrier is one of the most impactful strategies for toxin removal, since a permeable gut allows harmful compounds to bypass the livers protective filtration entirely

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Data availability All datasets generated and analyzed during this study are presented in this published article

CRISPR/Cas9-mediated glycolate oxidase disruption is an efficacious and safe treatment for primary hyperoxaluria type I