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Almost simultaneously, these cells showed a significantly increased cellular efficiency to produce ROS after stimulation, as determined by an SI calculated from the unstimulated and stimulated fluorescence intensity of ROS-producing PMN

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The roles of CBS and CSE in neoangiogenesis have been shown for different cancer types, and possibly involve per-sulphidation of KATP channels and the activation of MAPK signalling pathways, 156,157,158,159,160 which have been demonstrated in endothelial cells

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( In the context of ocular diseases, iron-dependent lipid peroxidation and ferroptosis have been linked to various retinal pathologies, including age-related macular degeneration (AMD), glaucoma, and diabetic retinopathy