Antidepressants (particularly mirtazapine, paroxetine, and some tricyclics), antipsychotics, corticosteroids, certain blood pressure medications (like beta-blockers), and some antihistamines taken regularly can all work against weight loss
Based on studies with other GLP-1 receptor agonists, these medications may enhance sodium excretion in renal tissues, potentially leading to mild diuresis
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Indeed, if semaglutide isn't refrigerated before first use, the active ingredients may degrade, causing the medication to not work as intended
Verified User Experience: One user noted improvement within one week of starting