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Secondly, ketone bodies are metabolized in mitochondria, resulting in less NAD + consumption and an increase in the NAD + /NADH ratio in the cytoplasm (144)

Int J Dev Neurosci 31:2124 Ribas GS, Manfredini V, de Mari JF, Wayhs CY, Vanzin CS, Biancini GB, Sitta A, Deon M, Wajner M, Vargas CR (2010) Reduction of lipid and protein damage in patients with disorders of propionate metabolism under treatment: a possible protective role of l-carnitine supplementation