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10.1093/brain/awq386 [DOI] [PubMed] [Google Scholar] 36.Scannevin RH, Chollate S, Jung MY, Shackett M, Patel H, Bista P, et al

The following measures can help manage injection site reactions: Applying a cold compress to the area, such as an ice pack, may help to reduce swelling

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They evidenced no superiority of one infiltrative method over the others, reporting only increased pain in the immediate post-infiltration period, most likely, according to the authors, induced by the leukocyte-mediated response in the group of patients receiving LR-PRP

doi: 10.1039/c3an01228j