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Madsen CD, Pedersen JT, Venning FA, Singh LB, Moeendarbary E, Charras G, Cox TR, Sahai E, Erler JT (2015) Hypoxia and loss of PHD2 inactivate stromal fibroblasts to decrease tumour stiffness and metastasis

Once reconstituted, it is injected subcutaneously through subcutaneous injection techniques

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In DKD, overexpression of GSDMD induces pyroptosis and reduces apoptosis, thereby switching from apoptosis to pyroptosis in TLR4-mediated renal TECs injury (137)

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