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(c) Are v forgetting the exceptionally LONG LIST of AE's of Sema & other GLP1a

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While the insulin receptor activates mainly the IP3k-PKB-ERK signaling cascade [88, 101], the GLP-1 and GIP receptors activate mainly the cAMP-PKA-CREB growth-factor signaling cascade in target cells (Fig

In adipose tissue, GIP promotes lipogenesis and fat storage under normal conditions