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By improving insulin sensitivity and reducing compensatory hyperinsulinaemia, these medications may help address the hormonal imbalances that drive androgen excess

Dosage adjustments or discontinuation may be warranted based on individual tolerance

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By the end of the trial (week 72), nearly half of women in all groups had shifted from obesity categories (body mass index 30 kg/m 2 ) to the overweight (body mass index 25 kg/m 2 ) or normal range weight categories (body mass index 18.5-24.9 kg/m 2 )