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We also thank Barbara Bassani, Daniela Farioli, Annalisa Bosi, Francesca Caudano and Matilde Tramacere for preliminary experiments

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Results: GHK-Cu treatment attenuated the CS-induced emphysematous changes and partially reversed the matrix metalloprotein -9 (MMP-9)/tissue inhibitor of metalloproteinases-1 (TIMP-1) imbalance in the lung tissue