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Apart from maintaining calcium channel homeostasis, GLP-1RAs also activate ATP-sensitive potassium channels to attenuate cardiac apoptosis and hypertrophy induced by pressure overload [166]

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Vagus nerve stimulation inhibits cytokine production and attenuates disease severity in rheumatoid arthritis

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Vitamin D toxicity is treatable, but severe cases may eventually cause kidney failure, irregular heartbeat, and calcification of soft tissues such as arteries

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Larger-scale, multi-center, placebo-controlled RCTs with important and conclusive outcome, for example PSE index, number of patients with improved clinical syndrome, are expected to identify the role of ALC therapy in HE

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