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Curr Immunol Rev

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Additionally, altered DSIP responses in major depression and suicidal patients suggest its role in addressing dysregulated stress in mood disorders (5)

When this pathway is overactive, it can lead to problems like genetic disorders

Figure 1: Changes in body weight from baseline to the end of treatment at week 26 associated with the trial product estimand, in the randomly assigned treatment groups administered either 0.3 mg of cagrilintide, 0.6 mg of cagrilintide, 1.2 mg of cagrilintide, 2.5 mg of cagrilintide, 4.5 mg of cagrilintide, 3.0 mg of liraglutide, or a placebo