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10.1177/019262339502300315 23 KauxJ

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Monitoring and Discontinuation: Users should monitor their response to BPC-157 and discontinue use if any concerning symptoms develop

Tregs take up lactate via MCT1 (encoded by Slc16a1), convert it to pyruvate for entry into the TCA, and generate phosphoenolpyruvate (PEP) via PEP carboxykinase (PEPCK), which feeds back to promote gluconeogenesis and nucleotide synthesis to support Treg proliferation