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Gene Ontology (GO) enrichment analysis showed that irradiation-induced differentially expressed genes(DEGs) were mainly enriched in biological processes such as inflammatory response, immune defense, cell apoptosis, and oxidative stress, and mainly involved cellular components such as the extracellular region, endoplasmic reticulum membrane, and proteasome complex, as well as molecular functions such as serine/threonine kinase activity and antioxidant activity (Fig

The compounds work differently enough that direct dose translation is not valid

First, most natural small molecules present low bioavailability problems [254], so further research on delivery systems and formulations for these drugs is needed

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