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While effective for symptom control, NSAIDs carry risks of gastrointestinal ulceration and bleeding, cardiovascular events, renal impairment, and impaired bone and tendon healing

We think our new work could lead to a clearable nanomedicine that can help detect liver injury much earlier with a simple blood test, and that could help a lot of people. The research was funded by the National Institutes of Healths NIDDK (R01DK103363 and R01DK115986), the Cancer Prevention and Research Institute of Texas, and The Welch Foundation

doi: 10.21203/rs.3.rs-1628424/v1

Campos LD, Almeida SantosPinentel VJD Jr, Carrega GLF, Cazarin CBB

Following the addition of GSH, we found that the expression levels of PAL, CAD and POD-related genes were all upregulated

The fat-soluble derivative Benfotiamine can be a more effective form for addressing depletion