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Carcinogenesis, 21 (3), 361370

Article 13

Inflammatory bowel disease (IBD), including Crohns disease and ulcerative colitis, may also cause systemic symptoms during bowel movements due to inflammation

Among these, the PI3K/Akt pathway is a prototypical pro-survival pathway (87)

Armonk, NY, United States)

There are no other officially reported contraindications specific to NAD+ as of now, but the absence of documented contraindications largely reflects limited clinical study