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The most defensible reading is to treat each compounds own within-trial data as its evidence and to treat any cross-compound ranking as a hypothesis, not a result
We always try to detect a small inotropic effect of cilostamide before we add other drugs that act via cAMP and are thus expected to be more effective in the presence of cilostamide
Masters CL, Bateman R, Blennow K, Rowe CC, Sperling RA, Cummings JL
While general evidence suggests no problems with male fertility on GLP-1 medications, individual situations might benefit from specialized guidance