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29,30 While a 2015 meta-analysis of 12 randomized controlled trials found treatment with antidepressants improved global IBS symptoms, a subgroup analysis found only TCAs, not SSRIs, were effective

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In a trial that compared participants taking 0.8, 1.6, and 2.4 grams per kilogram (or 0.36, 0.72, and 1.04 grams per pound) per day, intake above 0.8 grams per kilogram of protein per day resulted in sparing of fat free mass and promotion of body fat loss

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