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Its oral bioavailability makes it practical for long-duration rodent feeding studies and Phase II clinical trials in conditions such as GH-deficient adults, hip fracture recovery models, and age-related sarcopenia research

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This is one reason these species are beneficial in the gut microbiome and in the vaginal microbiome.[ref] Other bacteria, such as a major colonic butyrate-producing bacterium called Faecalibacterium prausnitzii, rely on riboflavin from food or other bacteria in the colon