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Implications for Development Phase 1 results informed dose selection for Phase 2 trials, identifying optimal dosing ranges that balanced efficacy with tolerability

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In cells in which cysteine 151 of Keap1 has been mutated to serine, nuclear accumulation and subsequent induction of Nrf2 target genes by sulforaphane is severely abrogated 18

ET to provide an overview of the trial and participant journey

Systemic: A Comparison for Researchers To help clarify the decision-making process for your research design, we've put together a simple comparison

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