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Weight loss was defined as the difference in weight recorded between Visit 2 (Week 0) and Visit 11 (Week 56)

Despite this promising anti-diabetic activity of TGR5 mediate by GLP-1 (345), its pharmacological activation in diabetic patients has shown side effects at the level of gallbladder and heart, hampering its clinical use (346)

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doi: 10.1007/s00125-016-3992-6 156 HalfordJC

Lumecca is primarily used for lightening skin on the face, but its also suitable for treating the neck, shoulders, chest, hands, arms, and legs