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The outstanding progress accomplished in the last years allows to assert that, even though the pathways implicated in the induction/execution of apoptosis have remained largely unaltered, many new redox-dependent processes have been added and we suggest the reading of several reviews on this subject (Anathy et al., 2012

The potential of GLP-1RAs to induce psychiatric adverse events is biologically plausible given the widespread expression of GLP-1 receptors in the central nervous system, 167 their influence on neurocognitive function, 168 and their effects on inflammation, stress response, and energy metabolism, which theoretically could improve mood

Gastroenterology 142:4654.e42

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NS3 is 67 kDa protein whose N-terminal has serine protease activity and whose C-terminal has NTPase/helicase activity